The reference libraryThe referencelibrary

Nicotinamide adenine dinucleotide · Coenzyme I · NAD · NAD plus

Longevity · Extensively studied

Functions as an obligate electron acceptor in catabolic oxidation and as the substrate consumed by NAD-dependent enzymes. Published work examines how the balance between synthesis via the salvage pathway and consumption by PARPs, sirtuins and CD38 determines the free pool available for oxidative phosphorylation.

Triple agonist · LY3437943 · Reta · GLP-1 triagonist

Weight Loss · Emerging

Characterised as engaging GIPR, GLP-1R and GCGR from one backbone. The glucagon arm is examined for hepatic effects on lipid handling and for its contribution to energy expenditure, which distinguishes the pharmacology from incretin-only agonists that act principally on insulin secretion and appetite pathways.

GRF(1-44) analogue · TH9507 · Tesamorelin acetate

Growth · Established

Described as binding the GHRH receptor on somatotrophs and raising intracellular cyclic AMP, increasing the amplitude of endogenous secretory pulses rather than imposing a continuous signal. The N-terminal modification is studied for the resistance to dipeptidyl peptidase-4 cleavage that extends the interval over which the analogue remains intact.

BPC-157 · TB-500 · Body Protection Compound-157 · Thymosin beta-4 fragment · Pentadecapeptide BPC 157 · Tβ4

Recovery · Extensively studied

BPC-157 is described in published models as upregulating vascular endothelial growth factor receptor 2 with downstream activity along the VEGFR2-Akt-eNOS axis, alongside modulation of the nitric oxide system and effects on focal adhesion kinase that underlie the fibroblast migration reported in tendon preparations. TB-500 is characterised as sequestering monomeric G-actin, shifting the polymerisation equilibrium and altering cytoskeletal turnover. The pairing is examined as angiogenic signalling and cytoskeletal mobilisation measured in one model.

CJC-1295 no-DAC with Ipamorelin · GHRH analogue blend · CJC-1295 · Ipamorelin

Growth · Established

CJC-1295 is characterised as engaging the GHRH receptor on somatotrophs, raising cyclic AMP and increasing the amplitude of secretory pulses. Ipamorelin is described as acting at GHS-R1a through a distinct Gq-coupled route, without the cortisol and prolactin cross-reactivity reported for earlier secretagogues. The two inputs are studied as additive rather than redundant.

Mitochondrial ORF of the 12S rRNA type-c · MOTSc · Mitochondrial-derived peptide

Metabolism · Established

Described as inhibiting the folate cycle and accumulating AICAR, which in turn activates AMPK. Under metabolic stress the peptide is reported to translocate to the nucleus and associate with stress-response transcription factors, positioning it as a signal between the mitochondrial and nuclear genomes.

Copper tripeptide-1 · Glycyl-L-histidyl-L-lysine copper · GHK · Copper peptide

Longevity · Extensively studied

The tripeptide is described as a physiological copper carrier, exchanging Cu(II) with albumin at a defined affinity and delivering it to cells. Downstream literature reports modulation of several hundred genes in fibroblast models, with particular attention to the balance between matrix metalloproteinases and their tissue inhibitors.

ACTH(4-10) analogue · N-acetyl semax · Semax acetate

Neuro · Established

Characterised as raising BDNF and NGF transcript levels in hippocampal and cortical preparations without the adrenocorticotropic activity of the parent fragment. Additional work examines effects on the dopaminergic and serotonergic systems and on markers of cerebral perfusion in ischaemia models.

Tuftsin analogue · TP-7 · Selank acetate

Neuro · Emerging

The proline-glycine-proline extension is described as conferring resistance to peptidase cleavage, extending the window over which the tuftsin core is available. Published work examines inhibition of enkephalin-degrading enzymes and changes in GABAergic and serotonergic gene expression in hippocampal preparations.

Acetyl octapeptide-3 · Acetyl glutamyl heptapeptide-3 · Acetyl octapeptide-1

Regeneration · Emerging

Described as competing with SNAP-25 for a position in the SNARE complex, so that the assembly forms less efficiently. The literature examines the consequence for vesicle docking and catecholamine release in cell models, and the acetylation at the N-terminus is studied for the stability it confers on a short sequence.

MT-2 · Melanotan 2 · MT2 · Melanocortin analogue

Performance · Established

Described as engaging melanocortin receptors with the conformational constraint of the cyclic lactam bridge holding the pharmacophore in an active orientation. Published work examines MC1R engagement in melanocyte preparations and MC3R and MC4R engagement in hypothalamic models, and treats the lack of subtype selectivity as the defining feature of the molecule.

Bacteriostatic water for injection · BAC water · Sterile water for injection · Diluent

Preparation · Established

The benzyl alcohol content is bacteriostatic rather than bactericidal: it inhibits microbial growth in the vial between entries. It is not an active compound and it has no pharmacology of its own in this context. Compatibility is the property that matters, and it is stated per compound on the certificate of analysis.